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GNF-5837, MedChemExpress

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MedChemExpress GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .

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€ 96.00 - € 738.00

Specifications

Chemical Name or Material GNF-5837
CAS 1033769-28-6
Color Orange
Purity Grade Notes Research
Molecular Formula C28H21F4N5O2
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Description

Description

GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .
Specifications

Specifications

GNF-5837
Orange
C28H21F4N5O2
O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2
535.49
Research
Cancer-Kinase/protease
1033769-28-6
Research
DMSO : ≥ 32 mg/mL (59.76 mM)
535.49
98.0%
Solid
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Safety and Handling

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

Documents

Product Certifications

Research purposes only

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