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GNF-5837, MedChemExpress
MedChemExpress GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .
Brand: Medchem Express HY-13491
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Description
GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .Specifications
| GNF-5837 | |
| Orange | |
| C28H21F4N5O2 | |
| DMSO : ≥ 32 mg/mL (59.76 mM) | |
| 535.49 | |
| 98.0% | |
| Solid |
| 1033769-28-6 | |
| Research | |
| 100 mg | |
| O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2 | |
| 535.49 | |
| Research | |
| Cancer-Kinase/protease |
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Product Title
GNF-5837, MedChemExpress
Research purposes only
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