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GNF-5837, MedChemExpress

MedChemExpress GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .

Brand:  Medchem Express HY-13491

Encompass

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Product Code. 16486196

  • € 738.00 / 100mg

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Description

Description

GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .
Specifications

Specifications

GNF-5837
Orange
C28H21F4N5O2
DMSO : ≥ 32 mg/mL (59.76 mM)
535.49
98.0%
Solid
1033769-28-6
Research
100 mg
O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2
535.49
Research
Cancer-Kinase/protease
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