General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ GeneBLAzer™ LXRβ-UAS-bla HEK 293T Cells
LXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-beta (LXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ Tango™ EDNRA-bla U2OS Cells
The Tango™ EDNRA-bla U2OS cells contain the human Endothelin Receptor A (EDNRA) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ SSTR5-bla U2OS DA Assay Kit
The Tango™ SSTR5-bla U2OS cells contain the human Somatostatin Receptor 5 (SSTR5) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15 HEK 293T DA Assay Kit
GeneBLAzer™ EDG3-Gα15 HEK 293T DA (Division Arrested) cells and EDG3-Gα15-NFAT-bla HEK 293T cells contain the human EDG3 receptor stably integrated in the GeneBLAzer™ Gα15-NFAT-bla HEK 293T cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line contains the promiscuous Gα protein, Gqo5, stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 Cells
GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells contain the human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ EDG6-bla U2OS DA Assay Kit
The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Gibco™ MRPs-BCRP Vesicular Transport Assay Reagent Set
MRPs-BCRP Vesicular Transport Assay Reagent Set
Thermo Scientific™ LanthaScreen™ ATF2 (19-106) A549 Cell Line
Contains a fusion protein consisting of GFP and a fragment encoding for aa 19-106 of ATF2 under the control of a CMV promotor
Thermo Scientific™ CellSensor™ CRE HEK 293T DA Assay Kit
The CellSensor™ CRE HEK 293T DA (Division Arrested) cells contains a beta-lactamase (bla) reporter gene under control of a cAMP response element (CRE) stably integrated into HEK293T cells.
Thermo Scientific™ Tango™ GPR21-bla U2OS Cells
Tango™ GPR21-bla U2OS cells contain the orphan human G-protein Coupled Receptor 21 (GPR21) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ GPR24-Gqi5-NFAT-bla CHO-K1 Cells
GeneBLAzer™ GPR24-Gqi5-NFAT-bla CHO-K1 cells contain the human Melanin-concetrating hormone receptor (GPR24) stably integrated into the GeneBLAzer™ Gqi5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ GALR2-bla U2OS Cells
The Tango™ GALR2-bla U2OS cells contain the human Galanin Receptor 2 (GALR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ IGF-1R GripTite™ Cell Line
The IGF-1R/PI3K/AKT pathway mediates signals for cell growth, cell survival, transcription, translation, and glucose uptake. IGF-1R is a receptor tyrosine kinase (RTK) that resides at the top of the pathway.