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Thermo Scientific™ CellSensor™ ISRE-bla HEK293T Cell Line

The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.

Brand:  Thermo Scientific™ K1655

Product Code. 10563084

  • € 11620.00 / Each

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Description

Description

Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway. The CellSensor™ ISRE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the interferon stimulated response element (ISRE). This cell line was engineered by transduction of the ISRE-bla construct into HEK 293T cells by lentivirus. Flow cytometry was then used to isolate a pool of clones responsive to interferon alpha a stimulation. A dose response curve for this assay against interferon alpha is available in the validation packet. Academic and non-profit customers, please inquire for special pricing.

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Specifications

Specifications

Cell-based beta lactamase reporter gene
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
CellSensor™
JAK/STAT (Type I IFN) pathway, TYK2, JAK1
CellSensor™
Dividing Cells
Cytokines, Signaling Pathway
1 Vial
Dividing Cells
Signaling Pathway
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Lot Number Certificate Type Date Catalog Number
Lot Number363409 Certificate TypeCertificate of Analysis Date15/04/2017 Catalog NumberK1655
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For Research Use Only. Not for use in diagnostic procedures.