Ultrasonic Homogenizers
Ultrasonic Homogenizers
Devices employing ultrasonic waves to homogenize samples; useful for disrupting cells/subcellular structures in suspension, and for creating emulsions. Available as handheld and benchtop models with a range of probe sizes and programming functions.
Also called sonicators, these devices use ultrasonic waves to homogenize samples and are used to prepare samples and create emulsions.
What Is an Ultrasonic Homogenizer?
Ultrasonic homogenizers are commonly used to disrupt cells and tissues via sound waves and the cavitation that they cause. The homogenizer tip vibrates rapidly, creating bubbles that form and collapse. This action tears apart any cells or particles in the solution.
An ultrasonic homogenizer consists of:
- A power generator and control
- A transducer or converter to change electric energy into high-frequency mechanical motion
- A probe or “horn,” typically made of titanium, which vibrates rapidly and longitudinally to transmit energy to the sample
What Are the Applications of an Ultrasonic Homogenizer?
- Create emulsions
- Disperse nanoparticles
- Reduce the size of suspended particles
- Break apart cells and subcellular structures in suspension
- Shear DNA (beneficial for some applications)
Are There Drawbacks to Using an Ultrasonic Homogenizer?
Unless it is first macerated and processed as a suspension, sonication does not work well for intact tissue. For gritty samples, use special horns or those with replaceable tips to prevent pitting.
Choose an ultrasonic homogenizer with enough power (wattage) to handle larger or more challenging samples or to process small samples quickly.
Sonication may not be compatible with temperature-sensitive samples because homogenizers generate a significant amount of heat.
The high-powered sound waves of ultrasonic homogenizers also create a hazard. At a minimum, wear ear protection or use in a separate area or inside a sound enclosure.
Fisherbrand™ Model 120 Sonic Dismembrator
Programable system ideal for small volume liquid processing. There are 3 probe size options available which allow for processing 0.2-50 mL volumes.
Fisherbrand™ Q705 Sonicator with Probe
Use this high powered sonicator for any application and sample volume. Fisherbrand™ Sonicators are ideal for cell disruption, nanoparticle dispersion, DNA shearing/ChIP and homogenization.
Fisherbrand™ Model 50 Sonic Dismembrator
Economical, small volume cell disruptor.
Fisherbrand™ 505 Sonicator with Probe
Use this high powered sonicator for various applications and sample volumes. Fisherbrand™ Sonicators with Probe are ideal for cell disruption, nanoparticle dispersion, homogenisation and sample preparation.
Branson Ultrasonics™ Sonifier™ SFX250/SFX550 Cell Disruptors
Advanced controls gives more precise control over all critical elements of experiment.
Branson Ultrasonics™ Sonifier™ SFX150 Cell Disruptor
Branson Ultrasonics Sonifier™ SFX150 Cell Disruptor with advanced controls gives more precise control over all critical elements of experiment.
Sonics Materials VC-505 Ultrasonic Processor
The VC-505 Ultrasonic Processor is extremely capable and versatile, it can safely process a wide range of organic and inorganic materials – from microliters to liters.
Fisherbrand™ Q705 Sonicator without Probe
Guarantees more efficient operation, sample-to-sample consistency and most importantly, a reliable end result. Fisherbrand™ Q705 Sonicator without Probe is the most technologically advanced sonicator available today.
Fisherbrand™ Q55 Sonicator without Probe
Effective for standard cell disruption and many other small-volume applications. Fisherbrand™ Q55 Sonicator is a compact and cost-effective ultrasonic processor that will occupy less bench space than any unit on the market.
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Fisherbrand™ Q500 Sonicator without Probe
Providing programmable operation and a digital display of operating parameters. Fisherbrand™ Q500 Sonicator without Probe is excellent for nanoparticle dispersion, creating emulsions, cell lysis and homogenization applications.
Sonics Materials VCX 750 Ultrasonic Microprocessor
The 750 Watt Ultrasonic Processor is for small and medium volume applications and is ideal for safely processing a wide range of organic and inorganic materials from 250 microliters to 1 liter.
Heidolph Instruments Boss Head
Suitable for stand rods with up to 13.1 mm maximum diameter
Sonics Materials VCX 500 Ultrasonic Microprocessor
Safely processes a wide range of organic and inorganic materials, from 250 microliters to 1 liter.
Sonics Materials VCX-130PB Ultrasonic Processor
Robust and reliable 130 watt Ultrasonic Processor with thumb-actuated pulser for small volume applications.
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