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  8. SSR 146977 hydrochloride, Tocris Bioscience™

SSR 146977 hydrochloride, Tocris Bioscience™

Product Code. 18095292
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Quantity:
10 mg
50 mg
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Description

Potent and selective NK3 antagonist

Potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide -induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM).

Chemical Identifiers

CAS 264618-38-4
Molecular Formula C35H43Cl3N4O2
Molecular Weight (g/mol) 658.105
InChI Key HYPKKQPFHSNZBY-GXUZKUJRSA-N
Synonym ssr 146977 hydrochloride, ssr 146977 hydrochloride/ssr-146977, n1-1-3-3r-1-benzoyl-3-3-3,4-dichlorophenyl-3-piperidinyl propyl-4-phenyl-piperidinyl-n,n-dimethylurea hydrochloride
PubChem CID 90488827
IUPAC Name 3-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-1,1-dimethylurea;hydrochloride
SMILES CN(C)C(=O)NC1(CCN(CC1)CCCC2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5.Cl

Specifications

Quantity 50 mg
Formula Weight 658.11
Percent Purity >98%
Chemical Name or Material SSR 146977 hydrochloride
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