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Pexidartinib, MedChemExpress
MedChemExpress Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.
€ 78.30 - € 451.50
Specifications
| Chemical Name or Material | Pexidartinib |
|---|---|
| CAS | 1029044-16-3 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C20H15ClF3N5 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16473197
|
Medchem Express
HY-16749 |
50 mg |
€ 249.75
50mg |
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|
16467166
|
Medchem Express
HY-16749 |
100 mg |
€ 306.45
100mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
16439707
|
Medchem Express
HY-16749 |
5 mg |
€ 78.30
5mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
16437178
|
Medchem Express
HY-16749 |
10 mg |
€ 108.00
10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
16411236
|
Medchem Express
HY-16749 |
200 mg |
€ 451.50
200mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.Specifications
| Pexidartinib | |
| White | |
| C20H15ClF3N5 | |
| DMSO : 100 mg/mL (239.34 mM; Need ultrasonic) | |
| 417.81 | |
| 98.0% | |
| Powder |
| 1029044-16-3 | |
| Research | |
| PLX-3397 | |
| FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F | |
| 417.81 | |
| Research | |
| Cancer-Kinase/protease |
Safety and Handling
H302∣H315∣H319∣H335
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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Product Title
Pexidartinib, MedChemExpress