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Pexidartinib, MedChemExpress
MedChemExpress Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.
Brand: Medchem Express HY-16749
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Description
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.Specifications
| Pexidartinib | |
| White | |
| C20H15ClF3N5 | |
| PLX-3397 | |
| FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F | |
| 417.81 | |
| Research | |
| Cancer-Kinase/protease |
| 1029044-16-3 | |
| Research | |
| 5 mg | |
| DMSO : 100 mg/mL (239.34 mM; Need ultrasonic) | |
| 417.81 | |
| 98.0% | |
| Powder |
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Product Title
Pexidartinib, MedChemExpress
Research purposes only
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