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NS 1643, Tocris Bioscience™

Product Code. 18065802
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

KV11.1 (hERG) channel activator; antiarrhythmic

Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM). Exhibits different molecular mechanisms of action at KV11.1 (hERG1) and KV11.2 (hERG2) channels. Displays antiarrhythmic activity in vitro.

Chemical Identifiers

CAS 448895-37-2
Molecular Formula C15H10F6N2O3
Molecular Weight (g/mol) 380.246
InChI Key NJFVQMRYJZHGME-UHFFFAOYSA-N
Synonym 1,3-bis 2-hydroxy-5-trifluoromethyl phenyl urea, unii-0i579cng0i, n,n'-bis 2-hydroxy-5-trifluoromethyl phenyl urea, urea, n,n'-bis 2-hydroxy-5-trifluoromethyl phenyl, 1,3-bis 2-hydroxy-5-trifluoromethylphenyl urea, ns hplc , solid
PubChem CID 10177784
IUPAC Name 1,3-bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea
SMILES C1=CC(=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)O)O

Specifications

Quantity 10 mg
Formula Weight 380.24
Percent Purity >98%
Chemical Name or Material NS 1643
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