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NCL 00017509, Tocris Bioscience™
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Quantity:
1 mg
Description
NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.
Specifications
Specifications
CAS | 1507367-00-1 |
Molecular Formula | C15H12N6O |
Linear Formula | C15H12N6O |
Quantity | 1 mg |
Synonym | 3-6-ethynyl-9h-purin-2-yl amino benzeneacetamide |
Solubility Information | Soluble to 100mM in DMSO |
InChI Key | CJQGLUJHMXCLQY-UHFFFAOYSA-N |
SMILES | C#CC1=C2C(=NC(=N1)NC3=CC=CC(=C3)CC(=O)N)N=CN2 |
IUPAC Name | 2-[3-[(6-ethynyl-7H-purin-2-yl)amino]phenyl]acetamide |
Molecular Weight (g/mol) | 292.302 |
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