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Tocris Bioscience™ GSK 2606414

Potent and selective PERK inhibitor; orally bioavailable

€ 378.00 - € 1540.00

Specifications

Purity >99%
Product Type GSK 2606414
Molecular Weight (g/mol) 451.44
Inhibitors GSK 2606414
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18065402
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Tocris Bioscience™
5107/10
10 mg
€ 378.00
10mg
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18776219
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Tocris Bioscience™
5107/50
50 mg
€ 1540.00
50mg
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Description

Description

Potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable.
Specifications

Specifications

>99%
GSK 2606414
451.44
GSK 2606414
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