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Tocris Bioscience™ GSK 2606414
Potent and selective PERK inhibitor; orally bioavailable
Brand: Tocris Bioscience™ 5107/50
1178.37 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
GSK 2606414 is a potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable.Specifications
| >99% | |
| GSK 2606414 | |
| GSK 2606414 |
| 50 mg | |
| 451.44 |
For Research Use Only