missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ GSK 1838705
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
€ 254.00 - € 1005.00
Specifications
| Purity | >98% |
|---|---|
| Product Type | GSK 1838705 |
| Molecular Weight (g/mol) | 532.57 |
| Inhibitors | GSK 1838705 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18708387
|
Tocris Bioscience™
5111/10 |
10 mg |
€ 254.00
10mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
18791368
|
Tocris Bioscience™
5111/50 |
50 mg |
€ 1005.00
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Potent insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) inhibitor (IC50 values are 1.6 and 2 nM, respectively). Also inhibits anaplastic lymphoma kinase (ALK) (IC50 = 0.5 nM). Displays > 800-fold selectivity for IR, IGFR1 and ALK over a panel of 44 kinases including JNK. Blocks proliferation of cancer cell lines in vitro, and causes complete regression of ALK-dependent tumors in vivo. Orally bioavailable.Specifications
| >98% | |
| GSK 1838705 | |
| 532.57 | |
| GSK 1838705 |
For Research Use Only