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Tocris™ CLP 290
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
Brand: Tocris™ 6758/50
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Description
CLP 290 is a K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).Specifications
| (Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2 H)-yl)thiazol-5(4 H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate | |
| 50 mg | |
| C19H21FN4O3S | |
| 98% |
| 1181083-81-7 | |
| KCC2 Activators | |
| 7828 |