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Tocris™ CLP 290

K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)

€ 275.37 - € 1078.81

Specifications

Chemical Name or Material (Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2 H)-yl)thiazol-5(4 H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate
CAS 1181083-81-7
Target KCC2 Activators
Molecular Formula C19H21FN4O3S
Purity 98%
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
18766866
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Tocris™
6758/10
10 mg
€ 275.37
10mg
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18787986
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Tocris™
6758/50
50 mg
€ 1078.81
50mg
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Description

Description

K+/Cl- Cotransporter 2 (KCC2) activator. Activates spinal inhibitory interneurons, restores physiological neuronal activity in the spinal cord and induces functional recovery in a mouse model of spinal cord injury. Also decreases blood vasopressin and glucose levels in mice with Streptozotocin (Cat. No. 1621) induced diabetes mellitus. Orally bioavailable prodrug of CLP 257 (Cat. No.5242).
Specifications

Specifications

(Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2 H)-yl)thiazol-5(4 H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate
KCC2 Activators
98%
1181083-81-7
C19H21FN4O3S
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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