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Tocris Bioscience™ A01

High affinity Smurf1 inhibitor; enhances BMP signaling

Brand:  Tocris Bioscience™ 5397/50

690.26 EUR valid until 2024-12-16
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Product Code. 18767078

  • € 872.00 / 50mg

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Description

Description

A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.
Specifications

Specifications

>98%
A01
A01
50 mg
512.93
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For Research Use Only