CAS RN 690206-97-4
CAS RN 690206-97-4
IUPAC Name:
N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Synonyms:
N-(4-chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
Molecular Weight (g/mol):
333.75
Molecular Formula:
C16H13ClFN3O2
InChi Key:
YHUIUSRCUKUUQA-UHFFFAOYSA-N
SMILES:
COC1=C(OC)C=C2C(NC3=C(F)C=C(Cl)C=C3)=NC=NC2=C1
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ZM 306416, MedChemExpress
MedChemExpress ZM-306416 (CB 676475) is a potent inhibitor of VEGFR with IC50s of 0.1 and 2 μM for KDR and Flt, respectively. ZM-306416 is also a EGFR inhibitor with an IC50 of <10 nM.