CAS RN 267243-28-7

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Canertinib, MedChemExpress

MedChemExpress Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	485.94
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	Canertinib
Grade	Research
SMILES	O=C(NC1=C(C=C2C(C(NC3=CC=C(C(Cl)=C3)F)=NC=N2)=C1)OCCCN4CCOCC4)C=C
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.02%
CAS	267243-28-7
Solubility Information	Ethanol : 12.5 mg/mL (25.72 mM; Need ultrasonic) ∣DMSO : 4.9 mg/mL (10.08 mM; Need warming)
Synonym	CI-1033 PD-183805
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₅ClFN₅O₃
Formula Weight	485.94

CAS RN 267243-28-7

CAS RN 267243-28-7

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