Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
Silencer™ Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry.
Silencer™ custom siRNAs (unmodified 21-bp duplexes) are cost-effective RNA interference (RNAi) tools ideal for knocking down gene expression in order to study protein function in a wide range of cell types.
Silencer™ Select siRNAs are the result of recent improvements in siRNA design combined with novel chemical modifications yielding unrivaled knockdown efficiency and specificity. Our best performing siRNA for cell culture work. Silencer™ siRNAs are unmodified 21 nucleotide siRNAs that have been designed with an older, yet rigorously tested design algorithm. A lower cost alternative to Silencer™ Select siRNAs, but without some of the performance enhancements.
Silencer™ Select siRNAs are the result of recent improvements in siRNA design combined with novel chemical modifications yielding unrivaled knockdown efficiency and specificity. Our best performing siRNA for cell culture work. Silencer™ siRNAs are unmodified 21 nucleotide siRNAs that have been designed with an older, yet rigorously tested design algorithm. A lower cost alternative to Silencer™ Select siRNAs, but without some of the performance enhancements.
DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
Silencer™ custom siRNAs (unmodified 21-bp duplexes) are cost-effective RNA interference (RNAi) tools ideal for knocking down gene expression in order to study protein function in a wide range of cell types.
Store at or below -20°C. Do not store in a frost-free freezer. (Dried oligonucleotides are shipped at ambient temperature.) Additional Materials Included: 1.75 mL Nuclease-free Water.
Description
GeneAssist - Custom Designed Silencer™ siRNA
Product Type
Custom Designed siRNA
Temperature (Metric)
Upon receipt, store in a non-frost-free freezer at or below -20°C
Silencer™ Select siRNAs are classic 21-mers which incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemistry.
The nuclear hormone receptor gene family includes receptors for thyroid and steroid hormones, retinoids and vitamin D, as well as receptors of unknown ligands.