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Invitrogen™ Zenon™ Alexa Fluor™ Plus IgG Labeling Reagents

Zenon Alexa Fluor Plus Labeling Reagents provide rapid, scalable antibody labeling and give a bright fluorescence-based indication of antibody binding when analyzed by flow cytometry, fluorescence microscopy, or high-content screening.

€ 594.00

Specifications

For Use With (Application) Antibody binding screening
Quantity 240 μL
Product Type Labeling Reagent
Content And Storage Store in refrigerator (2–8°C) and protect from light.
Detection Method Fluorescence
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Products 6
Product Code Brand Label or Dye Species Color Excitation/Emission Price Quantity & Availability  
Product Code Brand Label or Dye Species Color Excitation/Emission Price Quantity & Availability  
17904711
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Invitrogen™
Z25615
Alexa Fluor™ Plus 488 Human Green 494/519 nm
€ 594.00
240µL
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17984711
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Invitrogen™
Z25619
Alexa Fluor™ Plus 488 Mouse Green 494/519 nm
€ 594.00
240µL
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17974691
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Invitrogen™
Z25616
Alexa Fluor™ Plus 594 Human Red 590/617 nm
€ 594.00
240µL
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17984691
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Invitrogen™
Z25620
Alexa Fluor™ Plus 594 Mouse Red 590/617 nm
€ 594.00
240µL
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17944711
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Invitrogen™
Z25617
Alexa Fluor™ Plus 647 Human Far-red 650/671 nm
€ 594.00
240µL
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17904721
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Invitrogen™
Z25621
Alexa Fluor™ Plus 647 Mouse Far-red 650/671 nm
€ 594.00
240µL
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Description

Description

Streamline therapeutic antibody discovery campaigns with Zenon Alexa Fluor Plus Labeling Reagents to screen for antibody binding. These reagents provide rapid, scalable antibody labeling and give a bright fluorescence-based indication of antibody binding when analyzed by flow cytometry, fluorescence microscopy, or high-content screening.

An effective cell-based screening model is critical for the success of therapeutic antibody discovery campaigns. This serves as an important filter in the early stages of drug development. Identifying antibodies with optimal binding profiles accelerates candidate selection and helps minimize false positives. The new Zenon Alexa Fluor Plus Labeling Reagents are prelabeled Fab fragments directed against the Fc portion of IgG antibodies. They are improved in three ways: superior pan-reactive Fab fragments, optimized bioconjugation, and next-generation fluorophores. These combine to provide superior signal to background, providing more confidence in screening results.

The Zenon Alexa Fluor Plus IgG Labeling Reagents contain sufficient material to label one to four 96-well plates, depending on the Zenon labeling reagent concentration used. Formation of the Fab–antibody complex occurs in less than 5 minutes. Only a small amount of starting material is needed, and the method is optimized for efficient labeling of antibodies in serum, ascites fluid, or hybridoma suspensions. The insights provided by these approaches have the potential to accelerate biotherapeutic lead generation and development.

Advantages of Zenon Alexa Fluor Plus IgG Labeling Reagents include:
Simplicity—No reagent purification is required
Accuracy—No wash steps or quenchers are needed, maximizing throughput
Speed—Labeled antibodies are typically ready to use in 5 minutes
Specificity—Dyes are designed for the specific detection of antibody binding

Preserve primary antibody function and affinity
Reactive dye labeling of primary antibodies can have unpredictable and undesirable outcomes. One of these is reduced binding affinity due to label addition in the binding pocket. The Zenon antibody labeling approach, which is targeted to the Fc tail, resolves this potential issue.

Try custom antibody conjugates
If the antibody conjugate you need is not available as one of our stocked products, we will prepare a custom antibody conjugate for you. Our custom conjugation service is efficient and confidential, and we stand by the quality of our work. We are ISO 9001:2000 certified.

Specifications

Specifications

Antibody binding screening
Labeling Reagent
Fluorescence
Zenon™
240 μL
Store in refrigerator (2–8°C) and protect from light.
Alexa Fluor
IgG
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SDS
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Documents

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