Invitrogen™ Vivid™ NADP+ , 10mM

Description

Vivid™ NADP+, 10 mM, is a Vivid™ CYP450 Screening Kit component consisting of 10 mM NADP+ in 100 mM potassium phosphate, pH 8.0. Vivid™ NADP+, 10 mM, is included in the Vivid™ screening kits, but may also be purchased separately.

More About Vivid™ CYP450 Screening Kits
Vivid™ CYP450 Screening Kits are high-throughput fluorescence-based assays for detection of enzyme-drug interactions and CYP450 inhibition. Vivid™ CYP450 Screening Kits include Vivid™ Substrate, Vivid™ Fluorescent Standard, reaction buffer, Vivid™ Regeneration System, NADP+, and CYP450 BACULOSOMES™ Plus Reagent. Vivid™ Fluorogenic Substrates are blocked dyes that yield minimal fluorescence signal until cleaved or hydroxylated. Oxidation at either of two potential sites releases the highly fluorescent product. CYP450 BACULOSOMES™ Plus Reagents are microsomes prepared from insect cells expressing a human CYP450 isozyme and human cytochrome P450 reductase. CYP450 BACULOSOMES™ Plus Reagents offer a distinct advantage over human liver microsomes in that only one CYP450 isozyme is expressed, thereby preventing metabolism by other CYP450s.

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For Research Use Only. Not for any animal or human therapeutic or diagnostic use.