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  6. VEGFR3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

VEGFR3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. p-7209848 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16830285 20 μL 20µL
16820285 150 μL 150µL
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Product Code. 16830285 Supplier Proteintech Supplier No. 207121AP20UL

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Description

Rabbit Polyclonal Antibody

The antibody is specific to FLT4.

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.

Specifications

Antigen VEGFR3
Applications Western Blot
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene FLT4
Gene Accession No. P35916, P35917
Gene Alias FLT 4, FLT4, FLT41, Fms like tyrosine kinase 4, fms related tyrosine kinase 4, LMPH1A, PCL, VEGFR 3, VEGFR3
Gene Symbols FLT4
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14257, 2324
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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