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trans-Ned 19, Tocris Bioscience™

Product Code. 18005642
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Quantity:
10 mg
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Description

NAADP antagonist; inhibits Ca2+ release

Nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM); also inhibits [32P]NAADP binding (IC50 = 0.4 nM). Fluorescently labels NAADP receptors in intact cells. Stereosiomer of cis-Ned 19 (Cat. No. 3953).
TRUSTED_SUSTAINABILITY

Specifications

CAS 1354235-96-3
Molecular Formula C30H31FN4O3
Quantity 10 mg
Synonym trans-ned 19, ned-19, trans-ned-19, 1r,3s-1-3-4-2-fluorophenyl piperazin-1-yl methyl-4-methoxyphenyl-2,3,4,9-tetrahydro-1h-pyrido 3,4-b indole-3-carboxylic acid, naadp antagonist, nicotinic acid adenine dinucleotide phosphate antagonist, 1r,3s-1-3-4-2-fluorophenyl piperazin-1-yl methyl-4-methoxyphenyl-2,3,4,9-tetrahydro-1h-beta-carboline-3-carboxylic acid
InChI Key FUHCEERDBRGPQZ-LBNVMWSVSA-N
SMILES COC1=C(C=C(C=C1)C2C3=C(CC(N2)C(=O)O)C4=CC=CC=C4N3)CN5CCN(CC5)C6=CC=CC=C6F
IUPAC Name (1R,3S)-1-[3-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
Molecular Weight (g/mol) 514.601
PubChem CID 1427628
Formula Weight 514.59
Percent Purity >98%
Chemical Name or Material trans-Ned 19
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