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TC-S 7005, Tocris Bioscience™

Product Code. 30002030
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Quantity:
10 mg
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Description

Potent and selective PLK2 inhibitor

Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.

Specifications

CAS 1082739-92-1
Color Cream
Molecular Formula C21H17N3O3
Quantity 10 mg
Synonym 2-amino-isoxazolopyridine, 9, 3-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl-isoxazolo 5,4-c pyridin-5-amine, 3-2h-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl pyrido 4,3-d 1,2 oxazol-5-amine
InChI Key DAAGOCSHXCDWDY-ZDUSSCGKSA-N
SMILES CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5
IUPAC Name 3-(1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-[1,2]oxazolo[5,4-c]pyridin-5-amine
Molecular Weight (g/mol) 359.385
PubChem CID 24971422
Formula Weight 359.38
Percent Purity >98%
Physical Form Solid
Chemical Name or Material TC-S 7005
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