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Thermo Scientific™ Tango™ GPR109A-bla U2OS Cells

The Tango™ GPR109A-bla U2OS cells contain the human Nicotinic Acid Receptor (GPR109A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

Brand:  Thermo Scientific™ K1791

Product Code. 10463075

  • € 12500.00 / Each
Estimated Shipment: 16-01-2025
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Description

Description

The Tango™ GPR109A-bla U2OS cells contain the human Nicotinic Acid Receptor (GPR109A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ GPR109A-bla U2OS cells are functionally validated for Z' and EC50 concentrations of Nicotinic Acid. In addition, Tango™ GPR109A-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_177551
Dividing Cells
Native Tail
FRET
GPR109A-bla U2OS cells, GPR109A-bla U2OS Assay Protocol, Certificate of Analysis
GeneBLAzer™, Tango™
End Point
GPR109A
U2OS
GPCR
Cell-based beta-arrestin recruitment
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ GPR109A-bla U2OS cells
• Tango™ GPR109A-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ GPR109A-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Fluorescence
GPR109A
Single Cell Clone Origin
8 x 106 Cells
BLA (Beta-Lactamase)
U2OS Cell
Tango™
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For Research Use Only. Not for use in diagnostic procedures.