missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organic acids and derivatives
  6. Carboxylic acids and derivatives
  7. Carboxylic acid amides
  8. SU 16f, Tocris Bioscience™

SU 16f, Tocris Bioscience™

Product Code. 18084512
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective PDGFRβ inhibitor

Potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM).

Chemical Identifiers

CAS 251356-45-3
Molecular Formula C24H22N2O3
Molecular Weight (g/mol) 386.451
InChI Key APYYTEJNOZQZNA-UHFFFAOYSA-N
Synonym su 16f, su-16f, 3-2,4-dimethyl-5-2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl-1h-pyrrol-3-yl-propionic acid, 3-2,4-dimethyl-5-2-oxo-6-phenyl-1,2-dihydro-3h-indol-3-ylidene methyl-1h-pyrrol-3-yl propanoic acid
PubChem CID 53396310
IUPAC Name 3-[2,4-dimethyl-5-[(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
SMILES CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O

Specifications

Quantity 50 mg
Formula Weight 386.44
Percent Purity >98%
Chemical Name or Material SU 16f
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.