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  8. SU 16f, Tocris Bioscience™

SU 16f, Tocris Bioscience™

Product Code. 18054322
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Quantity:
10 mg
50 mg
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Description

Potent and selective PDGFRβ inhibitor

Potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM).

Chemical Identifiers

CAS 251356-45-3
Molecular Formula C24H22N2O3
Molecular Weight (g/mol) 386.451
InChI Key APYYTEJNOZQZNA-UHFFFAOYSA-N
Synonym su 16f, su-16f, 3-2,4-dimethyl-5-2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl-1h-pyrrol-3-yl-propionic acid, 3-2,4-dimethyl-5-2-oxo-6-phenyl-1,2-dihydro-3h-indol-3-ylidene methyl-1h-pyrrol-3-yl propanoic acid
PubChem CID 53396310
IUPAC Name 3-[2,4-dimethyl-5-[(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
SMILES CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O

Specifications

Quantity 10 mg
Formula Weight 386.44
Percent Purity >98%
Chemical Name or Material SU 16f
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