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SB 747651A dihydrochloride, Tocris Bioscience™ Product Code.: 30001551
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SB 747651A dihydrochloride, Tocris Bioscience™

Product Code. 30001551
10 mg
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Quantity:
10 mg
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Product Code. 30001551

Brand: Tocris Bioscience 4630/10

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Description

Potent MSK1 inhibitor; also inhibits other AGC group kinases

Potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay); targets the N-terminal kinase domain. Inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells. Blocks IL-10 production in macrophages.
TRUSTED_SUSTAINABILITY

Specifications

CAS 1781882-72-1
Molecular Formula C16H24Cl2N8O
Quantity 10 mg
Synonym sb 747651a dihydrochloride, 2-4-amino-1,2,5-oxadiazol-3-yl-1-ethyl-n-4-piperidinyl-1h-imidazo 4,5-c pyridine-7-methanamine dihydrochloride
InChI Key NRRCQHARLPNLHJ-UHFFFAOYSA-N
SMILES CCN1C2=C(C=NC=C2CNC3CCNCC3)N=C1C4=NON=C4N.Cl.Cl
IUPAC Name 4-[1-ethyl-7-[(piperidin-4-ylamino)methyl]imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine;dihydrochloride
Molecular Weight (g/mol) 415.323
PubChem CID 90488958
Formula Weight 415.32
Percent Purity >98%
Chemical Name or Material SB 747651A dihydrochloride
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