missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organopnictogen compounds
  6. SAHA, Tocris Bioscience™

SAHA, Tocris Bioscience™

Product Code. 30001593
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Class I and II HDAC inhibitor

SAHA inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro. Activates autophagy. SAHA increases efficiency of transcription factor-induced reprogramming of mouse embryonic fibroblasts (MEF) to induced pluripotent stem cells (iPSC). Also enhances adeno-associated virus transduction of HeLa cells.

Chemical Identifiers

CAS 149647-78-9
Molecular Formula C14H20N2O3
Molecular Weight (g/mol) 264.325
InChI Key WAEXFXRVDQXREF-UHFFFAOYSA-N
Synonym vorinostat, saha, suberoylanilide hydroxamic acid, zolinza, n-hydroxy-n'-phenyloctanediamide, suberanilohydroxamic acid, n1-hydroxy-n8-phenyloctanediamide, saha cpd, vorinostat usan, octanediamide, n-hydroxy-n'-phenyl
PubChem CID 5311
ChEBI CHEBI:45716
IUPAC Name N'-hydroxy-N-phenyloctanediamide
SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO

Specifications

Quantity 50 mg
Formula Weight 264.32
Percent Purity >98%
Chemical Name or Material SAHA
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.