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Retinoic acid, Tocris Bioscience™

Product Code. 30001113
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Endogenous retinoic acid receptor agonist

Retinoic acid is an endogenous agonist for retinoic acid receptors (IC50 = 14 nM for RARα, RARβ and RARγ receptors). Also promotes differentiation of mouse embryonic stem cells (ESCs) into adipocytes, neurons and glia in vitro. Proposed ligand of RORβ (Kd = 280 nM). Activates autophagy.

For more information about how Retinoic acid may be used, see our protocols: Generation of β cells from hPSCs, Cultivating Cerebral Organoids .

Specifications

CAS 302-79-4
Molecular Formula C20H28O2
MDL Number MFCD00001551
Quantity 50 mg
Synonym retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra
InChI Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
IUPAC Name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular Weight (g/mol) 300.44
PubChem CID 444795
ChEBI CHEBI:15367
Formula Weight 300.44
Percent Purity >99%
Chemical Name or Material Retinoic acid
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