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Retinoic acid, Tocris Bioscience™

Product Code. 30001113
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

Endogenous retinoic acid receptor agonist

Retinoic acid is an endogenous agonist for retinoic acid receptors (IC50 = 14 nM for RARα, RARβ and RARγ receptors). Also promotes differentiation of mouse embryonic stem cells (ESCs) into adipocytes, neurons and glia in vitro. Proposed ligand of RORβ (Kd = 280 nM). Activates autophagy.

For more information about how Retinoic acid may be used, see our protocols: Generation of β cells from hPSCs, Cultivating Cerebral Organoids .

Specifications

CAS 302-79-4
Molecular Formula C20H28O2
MDL Number MFCD00001551
Quantity 50 mg
Synonym retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra
InChI Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
IUPAC Name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Molecular Weight (g/mol) 300.44
PubChem CID 444795
ChEBI CHEBI:15367
Formula Weight 300.44
Percent Purity >99%
Chemical Name or Material Retinoic acid
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