Thermo Scientific™ Wellcogen™ Neisseria meningitidis B/E. coli K1 Rapid Latex Agglutination Test

Description

Wellcogen™ N. meningitidis B/E. coli K1 is a rapid latex test for use in the qualitative detection of antigen from Neisseria meningitidis (meningococcus) group B and Escherichia coli K1, present in body fluids as a consequence of infection. The latex can also be used for the detection of specific antigen in blood culture supernatants and for the identification of meningococcus group B or E. coli K1 cultures. Meningococcus group B antigen and E. coli K1 antigen are immunologically indistinguishable from each other. NOTE: Tests performed directly on clinical specimens are intended for screening purposes and should augment, not replace, culture procedures. Results must be used in conjunction with other data; eg symptoms, results of other tests, clinical impressions etc.

Use this rapid latex test in the qualitative detection of antigen from Neisseria meningitidis (meningococcus) group B and Escherichia coli K1 present in body fluids as a consequence of infection.

The latex can also be used for the detection of specific antigen in blood culture supernatants and for the identification of meningococcus group B or E. coli K1 cultures.

The reagent consists of polystyrene latex particles which have been coated with monoclonal antibodies specific to meningococcus group B antigen. These latex particles agglutinate in the presence of sufficient homologous antigen. N.B. The polysaccharide K1 antigen of E. coli shows structural and immunological identity with meningococcus group B antigen, and the reagent does not distinguish between them. Therefore, the reagent may be used to assist in the diagnosis of meningococcal meningitis and neonatal E. coli meningitis.

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