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R&D Systems™ Recombinant Mouse VSIG4 Fc Chimera Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.
Brand: R&D Systems™ 4674-VS-050
This item is not returnable.
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Description
Measured by its ability to inhibit anti-CD3-induced proliferation of splenic T lymphocytes. Vogt, L. et al. (2006) J. Clin. Invest. 116:2817. The presence of immobilized Recombinant Mouse VSIG4 Fc Chimera inhibited the anti-CD3 response by =50%. The ED50 for this effect is 1.25-5 μg/mL.Specifications
| NP_808457 | |
| Lyophilized from a 0.2 μm filtered solution in PBS. | |
| M.W. (Observed): 60-65 kDa, reducing conditions; M.W. (theoretical): 46 kDa (monomer) | |
| 50 μg | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
| <1.0 EU / 1 μg of the protein by the LAL method. | |
| Unconjugated | |
| Reconstitute at 200 μg/mL in sterile PBS. | |
| VSIG4 |
| Bioactivity | |
| 11326 | |
| VSIG4 Fc Chimera | |
| Mouse myeloma cell line, NS0-derived mouse VSIG4 protein Mouse VSIG4 (His20-Pro187) (N-terminus) Accession # NP_808457 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus) | |
| Disulfide-linked homodimer | |
| Vsig4 | |
| Recombinant | |
| >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining. |
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