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R&D Systems™ Recombinant Mouse S100A8/S100A9 Heterodimer Protein

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Brand:  R&D Systems™ 8916-S8-050

Product Code. 18388947

  • € 529.00 / 50µg

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Description

Description

The Recombinant Mouse S100A8/S100A9 Heterodimer Protein is derived from E. coli. The Recombinant Mouse S100A8/S100A9 Heterodimer Protein has been validated for the following applications: Bioactivity.
Specifications

Specifications

Bioactivity
50 μg
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
S100A8/S100A9 Heterodimer
Unconjugated
Recombinant
>95%, by SDS-PAGE with Silver Staining
Observed M.W.: 7kDa and 12kDa, reducing conditions, Theoretical M.W.: 10kDa (S100A8), 13kDa (S100A9)
E. coli-derived mouse S100A8/S100A9 Heterodimer protein, (N-terminus) Mouse S100A8 (Pro2-Glu89) Accession &Num; P27005 Mouse S100A9 (Ala2-Lys113) Accession &Num; P31725 (C-terminus)
<0.10 EU per 1μg of the protein by the LAL method.
Measured by its ability to induce IL-6 secretion by A375 human melanoma cells. Hibino, T. et al. (2013) Cancer Res. 73:172. The ED50 for this effect is typically 1.5-6μg/mL.
Mouse
E. coli-derived Mouse S100A8 (Pro2-Glu89) Accession # P27005, N-terminal; Mouse S100A9 (Ala2-Lys113) Accession # P31725, C-terminus
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