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R&D Systems™ Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
Brand: R&D Systems™ 7126-B7-050
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Description
Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 1-6 μg/mL.Specifications
| AAH20568 | |
| Lyophilized from a 0.2 μm filtered solution in PBS. | |
| M.W. (Observed): 64-75 kDa, reducing conditions; M.W. (theoretical): 44.8 kDa (monomer) | |
| 50 μg | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
| <0.01 EU / 1 μg of the protein by the LAL method. | |
| Unconjugated | |
| Reconstitute at 200 μg/mL in PBS. | |
| VISTA/B7-H5/PD-1 H |
| Bioactivity | |
| 64115 | |
| Gi24/VISTA/B7-H5 Fc Chimera | |
| Mouse myeloma cell line, NS0-derived human VISTA/B7-H5/PD-1 H protein Human VISTA/B7-H5/PD-1 H (Phe33-Ala194) (N-terminus) Accession # AAH20568 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus) | |
| Disufide-linked homodimer | |
| C10orf54 | |
| Recombinant | |
| >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining. |
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