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R&D Systems™ Caspase-3 Inhibitor Z-DEVD-FMK

Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Caspase-3 Inhibitor Z-DEVD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.

Brand:  R&D Systems™ FMK004

Product Code. 18370398

  • € 347.00 / 1mg

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Description

Description

  • Fluoromethyl ketone (FMK)-derivatized peptides are useful tools for studying caspase activity
  • Used in tissue cultures to inhibit apoptosis at final working concentrations of 50nM to 100μM
  • Regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, IAP, BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin and BIRC7/Livin
Specifications

Specifications

Store the unopened product at -20 to -70° C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Caspase-3
Z-DEVD-FMK
1 mg
668Da
Lyophilized
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For research use only. Not for use in diagnostic procedures