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Tocris Bioscience™ Pyridostatin pentahydrochloride
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
€ 308.00
Specifications
| CAS | 1781882-65-2 |
|---|---|
| Product Type | Pyridostatin pentahydrochloride |
| Inhibitors | Pyridostatin pentahydrochloride |
Description
Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).Specifications
| 1781882-65-2 | |
| Pyridostatin pentahydrochloride | |
| Pyridostatin pentahydrochloride |
For Research Use Only