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Prednisolone, 99%, Thermo Scientific Chemicals Product Code.: 13521640
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Prednisolone, 99%, Thermo Scientific Chemicals

Product Code. 13521640
25 g, Glass Bottle
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Quantity:
1 g
5 g
25 g
Packaging:
Glass Bottle
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Product Code. 13521640

Brand: Thermo Scientific Acros 449470250

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Description

Prednisolone, or metacortandralone, CAS # 50-24-8, is a synthetic glucocorticoid.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Prednisolone is a derivative of prednisone with an oxo to beta-hydroxy reduction at position 11

• Prednisolone binds cell surface receptors and is transported to the nucleus, where it binds certain nuclear receptors responsible for transcription of proinflammatory cytokines

Applications

• Prednisolone can be used for laboratory research on tumor growth and prevention

• Prednisolone may also be used for developmental and endocrine research, in vivo or in vitro

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-24-8
Molecular Formula C21H28O5
Molecular Weight (g/mol) 360.44
InChI Key OIGNJSKKLXVSLS-VWUMJDOOSA-N
Synonym prednisolone, metacortandralone, hydroretrocortine, predonine, deltacortril, meticortelone, deltahydrocortisone, prenolone, hydroretrocortin, delta-cortefShow MoreShow Less
PubChem CID 5755
ChEBI CHEBI:8378
IUPAC Name (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-oneShow MoreShow Less
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O

Specifications

Melting Point 240.0°C
Assay Percent Range 98.5% min. (HPLC)
Packaging Glass Bottle
Quantity 25 g
Merck Index 15,7841
Solubility Information Solubility in water: slightly soluble. Other solubilities: soluble in methanol, dioxane, slightly soluble in acetone, chloroform,, ethylacetate
Formula Weight 360.44
Percent Purity 99%
Chemical Name or Material Prednisolone

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberA0456683 Certificate TypeCertificate of Analysis Date02/10/2023 Catalog Number449470050,449470250,449470010
Lot NumberA0422476 Certificate TypeCertificate of Analysis Date02/05/2023 Catalog Number449470050,449470250,449470010
Lot NumberA0400003 Certificate TypeCertificate of Analysis Date14/12/2022 Catalog Number449470050,449470250,449470010
Lot NumberA0410031 Certificate TypeCertificate of Analysis Date13/12/2022 Catalog Number449470050,449470250,449470010
Lot NumberA0374358 Certificate TypeCertificate of Analysis Date13/12/2022 Catalog Number449470050,449470250,449470010

Safety and Handling

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Product Identifier
  • Prednisolone
 Signal Word
  • Danger
 Hazard Category
  • Reproductive toxicity Category 1B
 Hazard Statement
  • H360D-May damage the unborn child.
 Precautionary Statement
  • P202-Do not handle until all safety precautions have been read and understood.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
SDS

RUO – Research Use Only

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