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  6. Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format
  7. 15971227

Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format

Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.

Brand:  Thermo Scientific™ A39268

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Product Code. 15971227

  • € 232.00 / Pack of 10
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Description

Description

Thermo Scientific™ Pierce Sulfo-SMCC is a very popular, water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 Ås).

  • Reactive groups: sulfo-NHS ester and maleimide
  • Reactive towards: amino and sulfhydryl groups
  • Water-soluble (compare to SMCC), so crosslinking can be done in physiologic solutions
  • High purity, crystalline reagent can be used to create high-purity maleimide-activated derivatives
  • Cyclohexane bridge confers added stability to the maleimide group making Sulfo-SMCC the ideal crosslinking agent for maleimide activation of proteins. Maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7 at 4°C.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Sulfhydryl
Sulfo-SMCC
No
Upon receipt store desiccated at -20°C.
Ambient
Chemical Labeling
Maleimide, Sulfo-NHS Ester
Solid
Water
Yes
No
436.37
8.3 Å
No
No-Weigh™
Heterobifunctional
Short (<10 Å)
10 x 2 mg
Standard, Single-use, Premium-grade
Crosslinker
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