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  6. Nitro Blue Tetrazolium chloride, 98+%, Thermo Scientific Chemicals

Nitro Blue Tetrazolium chloride, 98+%, Thermo Scientific Chemicals

Product Code. 15463029
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Quantity:
1 g
5 g
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This item is not returnable. View return policy

Description

Intense blue dye used in histochemistry determinations

Intense blue dye used in histochemistry determinations.Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Intense blue dye used in histochemistry determinations.Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.

Solubility
Soluble in water, ethanol and methanol.

Notes
Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 298-83-9
Molecular Formula C40H30Cl2N10O6
Molecular Weight (g/mol) 817.644
MDL Number MFCD00012159
InChI Key FSVCQIDHPKZJSO-UHFFFAOYSA-L
Synonym Nitro BT; Nitrotetrazolium Blue chloride
PubChem CID 9281
ChEBI CHEBI:9505
IUPAC Name 2-[2-methoxy-4-[3-methoxy-4-[3-(4-nitrophenyl)-5-phenyltetrazol-2-ium-2-yl]phenyl]phenyl]-3-(4-nitrophenyl)-5-phenyltetrazol-2-ium;dichloride
SMILES COC1=C(C=CC(=C1)C2=CC(=C(C=C2)[N+]3=NC(=NN3C4=CC=C(C=C4)[N+](=O)[O-])C5=CC=CC=C5)OC)[N+]6=NC(=NN6C7=CC=C(C=C7)[N+](=O)[O-])C8=CC=CC=C8.[Cl-].[Cl-]

Specifications

Melting Point ∼190°C (decomposition)
Beilstein 4115923
Solubility Information Soluble in water,ethanol and methanol.
Formula Weight 817.65
Percent Purity 99%
Sensitivity Light sensitive
Color Yellow
Quantity 5 g
Physical Form Crystalline Powder
Chemical Name or Material Nitro Blue Tetrazolium chloride

Safety and Handling

compliance-icons
Product Identifier
  • Nitro Blue Tetrazolium chloride
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
 Supplemental information
  • MIXTURE LIST-Contains : Nitro Blue Tetrazolium chloride

RUO – Research Use Only

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