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Tocris Bioscience™ NF 110
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Product Code. 18085792
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18085792

Brand: Tocris Bioscience™ 2548/10

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This item is not returnable. View return policy

Description

Potent P2X3 antagonist

High affinity P2X3 receptor antagonist (Ki values are 36, 82 and 4144 nM for P2X3, P2X1 and P2X2 recombinant receptors respectively). Shows no activity at P2Y1, P2Y2 and P2Y11 receptors (IC50 > 10 μM). Potently inhibits α,β-meATP-evoked desensitizing currents in rat DRG neurons (IC50 = 527 nM). Shows antitumor activity against several tumor types. Also inhibits DNA-binding activity of HMGA2 (IC50 = 0.87 μM).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 111150-22-2
Molecular Formula C41H28N6Na4O17S4

Specifications

Quantity 10 mg
Formula Weight 1096.9
Purity >98%
Molecular Weight (g/mol) 1096.899
Chemical Name or Material NF 110
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