missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Proteintech™ Mouse CCL3 ELISA Kit
KE10023 is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The Mouse CCL3 ELISA kit is to be used to detect and quantify protein levels of endogenous mouse CCL3.
Brand: Proteintech™ KE10023-96T
This item is not returnable.
View return policy
Description
- The assay recognizes mouse CCL3. An antibody specific for mouse CCL3 has been pre-coated onto the microwells. The mouse CCL3 protein in samples is captured by the coated antibody after incubation.
- Following extensive washing, another antibody of biotinylated specific for mouse CCL3 is added to detect the captured mouse CCL3 protein.
- For signal development, Streptavidin-HRP is added, followed by Tetramethyl-benzidine (TMB) reagent. Solution containing sulfuric acid is used to stop color development and the color intensity which is proportional to the quantity of bound protein is measurable at 450 nm with the correction wavelength set at 630 nm.
- Chemokine (C-C motif) ligand 3 (CCL3), also known as MIP-1 alpha, belongs to the family of chemokines. CCL3 has been found in the central nervous system and its cognate receptors, CCR1 and CCR5, have been reported to be expressed by astrocytes, microglia and neurons. CCL3 and its receptors, CCR1 and CCR5, also contribute to the development of bone disease in multiple myeloma by supporting tumor growth and regulating osteoclast differentiation.
- CCL3 is also associated with the regulation of cell growth, angiogenesis, and metastasis of different tumors such as melanoma, renal cell carcinoma, and colorectal cancer.
- Moreover, CCL3 enhances cell migration and metastasis by up-regulating matrix metalloproteinase-2 (MMP)-2 expression in chondrosarcoma cells.
Specifications
| NP_035467 | |
| 0.03 pg/mL | |
| Sandwich ELISA, Double Antibody | |
| Plasma, Serum | |
| Mouse | |
| Mouse | |
| <10% | |
| Blue ice | |
| 4.5 hr. |
| 1.95 to 125 pg/mL | |
| ISO 13485 | |
| Coated ELISA Kit | |
| DAB | |
| 20302 | |
| Solid | |
| <10% | |
| -20°C to +4°C | |
| P10855 |
Product Suggestions
Customers who viewed this item also viewed
Viewing 1-4 of
-
Catalog No. 12559069
183,00 € / Pack of 10 -
Catalog No. 15955590
263,00 € / 30 reactions -
Catalog No. 10516495
137,00 € / 1mL -
Catalog No. 10017003
114,00 € / 100mL -
Catalog No. 10729174
311,00 € / 500µL -
Catalog No. 15137105
9.870,00 € / Each -
Catalog No. 11514270
862,00 € / 100µL -
Catalog No. 10390964
718,00 € / 1 set -
Catalog No. 15642299
612,00 € / 96 tests -
Catalog No. 15880712
528,00 € / Pack of 2
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- 96TEST Mouse CCL3 ELISA Kit
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 1
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H302-Harmful if swallowed.
- H315-Causes skin irritation.
- H318-Causes serious eye damage.
- H319-Causes serious eye irritation.
- H332-Harmful if inhaled.
- H335-May cause respiratory irritation.
Precautionary Statement
- P201-Obtain special instructions before use.
- P202-Do not handle until all safety precautions have been read and understood.
- P234-Keep only in original container.
- P264-Wash skin thoroughly after handling.
- P270-Do not eat, drink or smoke when using this product.
- P273-Avoid release to the environment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
- P330-Rinse mouth.
- P362-Take off contaminated clothing.
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : Sulphuric Acid, Tetramethylbenzidine
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Proteintech™ Mouse CCL3 ELISA Kit > Target Species: Mouse
Spot an opportunity for improvement?Share a Content Correction
