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Tocris Bioscience™ ML 297
Selective Kir3.1/3.2 (GIRK1/2) channel activator
Brand: Tocris Bioscience™ 5380/50
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Description
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). Exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters. Prevents PTZ -induced epileptic seizures in mice. Brain penetrant.Specifications
>99% | |
ML 297 | |
ML 297 |
50 mg | |
328.32 |
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