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Tocris Bioscience™ ML 297

Selective Kir3.1/3.2 (GIRK1/2) channel activator

Brand:  Tocris Bioscience™ 5380/50

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Product Code. 18773148

  • € 845.00 / 50mg

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Description

Description

ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). Exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters. Prevents PTZ -induced epileptic seizures in mice. Brain penetrant.
Specifications

Specifications

>99%
ML 297
ML 297
50 mg
328.32
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