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Tocris Bioscience™ (±)-ML 209

RORγt inverse agonist; suppresses Th17 cell differentiation

Specifications

Color White
Product Type Inhibitor
CAS 1334526-14-5
Molecular Formula C25H31NO6
Solubility Soluble to 100mM in DMSO
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
18791068
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Tocris Bioscience™
5987/10
10 mg N/A
N/A
18736658
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Tocris Bioscience™
5987/50
50 mg N/A
N/A
Description

Description

RORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).
Specifications

Specifications

White
1334526-14-5
Soluble to 100mM in DMSO
Inhibitor
C25H31NO6
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For Laboratory Research Use Only