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LMX1A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA534470
This item is not returnable.
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Description
A suggested positive control is rat brain tissue lysate. PA5-34470 can be used with blocking peptide PEP-1512.
The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
Specifications
| LMX1A | |
| Polyclonal | |
| Unconjugated | |
| Lmx1a | |
| dr; dreher; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1, alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX1; LMX-1; Lmx1.1; LMX-1.1; Lmx1a; MGC87616; shaker short-tail; sst | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 110648, 289201, 4009 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q8TE12, Q9JKU8 | |
| Lmx1a | |
| A 16 amino acid peptide near the carboxy terminus of human LMX1A | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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