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LMX1A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA5115517
This item is not returnable.
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Description
Antibody detects endogenous levels of total LMX1A.
The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
Specifications
| LMX1A | |
| Polyclonal | |
| Unconjugated | |
| Lmx1a | |
| dr; dreher; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1, alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX1; LMX-1; Lmx1.1; LMX-1.1; Lmx1a; MGC87616; shaker short-tail; sst | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 110648, 289201, 4009 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide | |
| Q8TE12, Q9JKU8 | |
| Lmx1a | |
| A synthesized peptide derived from human LMX1A(Accession Q8TE12), corresponding to amino acid residues R152-L202. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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