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Invitrogen™ IL-2 Monoclonal Antibody (8D5)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA517097
Description
MA5-17097 targets IL-2 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-17097 immunogen is purified recombinant fragment of IL2 expressed in E. Coli. MA5-17097 detects IL-2 which has a predicted molecular weight of approximately 17.6kDa.
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Specifications
| IL-2 | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| P60568 | |
| IL2 | |
| Purified recombinant IL2 expressed in E. Coli. | |
| RUO | |
| 3558 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Western Blot | |
| 8D5 | |
| Unconjugated | |
| IL2 | |
| aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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