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Invitrogen™ Human ZIP1 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP1180
94.00 EUR valid until 2025-03-21
Use promo code "24111" to get your promotional price.
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price
Description
ZIP1 Synthetic Peptide, PEP-1180, from Invitrogen.
ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappa-B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
Specifications
27173 | |
purified | |
Human ZIP1 | |
-20°C | |
Liquid | |
Blocking Assay, Control | |
No | |
Peptide | |
RUO - research use only |
Human | |
Q9NY26 | |
200 μg/mL | |
Synthetic Peptide | |
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
SLC39A1 | |
0.02% sodium azide | |
50 μg | |
PBS |
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