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Invitrogen™ Human NPL (aa 47-106) Control Fragment Recombinant Protein

Product Code. 30195898
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30195898

Brand: Invitrogen™ RP109500

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140278 (PA5-140278. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9BXD5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 80896
Name Human NPL (aa 47-106) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 0610033B02Rik; C112; C1orf13; dihydrodipicolinate synthetase homolog 1; N-acetylneuraminate lyase; N-acetylneuraminate pyruvate lyase; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NAL; NALase; Npl; NPL1; Sialate lyase; sialate-pyruvate lyase; Sialic acid aldolase; sialic acid lyase
Common Name NPL
Gene Symbol NPL
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence FVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGAD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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