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Invitrogen™ Human GP6 Synthetic Peptide

Synthetic Peptide

Brand:  Invitrogen™ PEP0703

94.00 EUR valid until 2025-03-21
Use promo code "24111" to get your promotional price.


Product Code. 15368910

  • € 141.00 / 50µg

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Alert:

To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price

This item is not returnable. View return policy

Description

Description

GPVI Synthetic Peptide, PEP-0703, from Invitrogen.

Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss. However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

51206
purified
Human GP6
-20°C
Liquid
Blocking Assay, Control
No
Peptide
RUO - research use only
Human
Q9HCN6
200 μg/mL
Synthetic Peptide
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
GP6
0.02% sodium azide
50 μg
PBS
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Invitrogen™ Human GP6 Synthetic Peptide > 50 μg; Unlabeled

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