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Invitrogen™ Human CBX4 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP1471
94.00 EUR valid until 2025-03-21
Use promo code "24111" to get your promotional price.
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price
Description
CBX4 Synthetic Peptide, PEP-1471, from Invitrogen.
Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
Specifications
8535 | |
purified | |
Human CBX4 | |
-20°C | |
Liquid | |
Blocking Assay, Control | |
No | |
Peptide | |
RUO - research use only |
Human | |
O00257 | |
200 μg/mL | |
Synthetic Peptide | |
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
CBX4 | |
0.02% sodium azide | |
50 μg | |
PBS |
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